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Reviewed January 2009
What is the official name of the MSX1 gene?
The official name of this gene is “msh homeobox 1.”
MSX1 is the gene's official symbol. The MSX1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MSX1 gene?
The MSX1 gene provides instructions for making a protein that regulates the activity of other genes. The MSX1 gene is part of a larger family of homeobox genes, which act during early development to control the formation of many body structures. Specifically, this gene is critical for the normal development of the teeth and other structures in the mouth. It may also be important for development of the fingernails and toenails.
Does the MSX1 gene share characteristics with other genes?
The MSX1 gene belongs to a family of genes called homeobox (homeoboxes).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the MSX1 gene related to health conditions?
Where is the MSX1 gene located?
Cytogenetic Location: 4p16.2
Molecular Location on chromosome 4: base pairs 4,859,665 to 4,863,936
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The MSX1 gene is located on the short (p) arm of chromosome 4 at position 16.2.
More precisely, the MSX1 gene is located from base pair 4,859,665 to base pair 4,863,936 on chromosome 4.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MSX1?
You and your healthcare professional may find the following resources about MSX1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MSX1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MSX1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.