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Reviewed May 2010
What is the official name of the MPLKIP gene?
The official name of this gene is “M-phase specific PLK1 interacting protein.”
MPLKIP is the gene's official symbol. The MPLKIP gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MPLKIP gene?
The MPLKIP gene (formerly known as C7orf11) provides instructions for making a protein called M-phase specific PLK1 interacting protein. The function of this protein is unclear. Based on its interaction with a protein called Plk1, the MPLKIP protein is thought to play a role in cell growth and division. In particular, it may help regulate the cell cycle, which is the cell's way of replicating itself in an organized, step-by-step fashion. Researchers speculate that the MPLKIP protein may also be involved in gene transcription, which is the first step in protein production.
How are changes in the MPLKIP gene related to health conditions?
Where is the MPLKIP gene located?
Cytogenetic Location: 7p14.1
Molecular Location on chromosome 7: base pairs 40,132,743 to 40,134,652
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The MPLKIP gene is located on the short (p) arm of chromosome 7 at position 14.1.
More precisely, the MPLKIP gene is located from base pair 40,132,743 to base pair 40,134,652 on chromosome 7.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MPLKIP?
You and your healthcare professional may find the following resources about MPLKIP helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MPLKIP gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MPLKIP?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.