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Reviewed January 2010
What is the official name of the MLYCD gene?
The official name of this gene is “malonyl-CoA decarboxylase.”
MLYCD is the gene's official symbol. The MLYCD gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MLYCD gene?
The MLYCD gene provides instructions for making an enzyme called malonyl-CoA decarboxylase. This enzyme helps regulate the formation and breakdown of a group of fats called fatty acids. Many tissues, including heart (cardiac) muscle, use fatty acids as a major source of energy. The body also uses fatty acids to build cell membranes, produce hormones, and carry out many other important processes.
Malonyl-CoA decarboxylase is responsible for the chemical reaction that converts a molecule called malonyl-CoA to a molecule called acetyl-CoA. This reaction is an important step in the breakdown of fatty acids. Acetyl-CoA is then used to make new fatty acids and can also be used to produce energy.
Malonyl-CoA decarboxylase is most active in cardiac muscle and in muscles used for movement (skeletal muscles). It is also found in other organs and tissues, including the brain, small intestine, liver, kidney, and pancreas. This enzyme probably functions in several parts of the cell, including mitochondria, which are cells' energy-producing centers, and peroxisomes, which are small sacs that process fatty acids and other molecules. Malonyl-CoA decarboxylase also functions in the fluid that surrounds these cell structures (the cytoplasm).
How are changes in the MLYCD gene related to health conditions?
Where is the MLYCD gene located?
Cytogenetic Location: 16q24
Molecular Location on chromosome 16: base pairs 83,899,125 to 83,916,182
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The MLYCD gene is located on the long (q) arm of chromosome 16 at position 24.
More precisely, the MLYCD gene is located from base pair 83,899,125 to base pair 83,916,182 on chromosome 16.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MLYCD?
You and your healthcare professional may find the following resources about MLYCD helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MLYCD gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MLYCD?
acids ; breakdown ; cardiac ; cardiomyopathy ; cell ; CoA ; coenzyme A ; cytoplasm ; deficiency ; enzyme ; fatty acids ; gene ; hypoglycemia ; intestine ; kidney ; mitochondria ; molecule ; pancreas ; peroxisomes
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.