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Reviewed May 2010
What is the official name of the MCM6 gene?
The official name of this gene is “minichromosome maintenance complex component 6.”
MCM6 is the gene's official symbol. The MCM6 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MCM6 gene?
The MCM6 gene provides instructions for making part of the MCM complex, a group of proteins that functions as a helicase. Helicases attach to particular regions of DNA and temporarily unwind the two spiral strands of these molecules. When a cell prepares to divide to form two cells, helicases unwind the DNA so that it can be copied. The DNA that makes up the chromosomes is duplicated (replicated) so that each new cell will get a complete set of chromosomes. Helicases are also involved in the production of RNA, a chemical cousin of DNA.
How are changes in the MCM6 gene related to health conditions?
Where is the MCM6 gene located?
Cytogenetic Location: 2q21
Molecular Location on chromosome 2: base pairs 135,839,625 to 135,876,476
The MCM6 gene is located on the long (q) arm of chromosome 2 at position 21.
More precisely, the MCM6 gene is located from base pair 135,839,625 to base pair 135,876,476 on chromosome 2.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about MCM6?
You and your healthcare professional may find the following resources about MCM6 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MCM6 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MCM6?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)