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Reviewed November 2006
What is the official name of the LHFPL5 gene?
The official name of this gene is “lipoma HMGIC fusion partner-like 5.”
LHFPL5 is the gene's official symbol. The LHFPL5 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the LHFPL5 gene?
The LHFPL5 gene (also called TMHS) provides instructions for making a protein called LHFP-like protein 5. The specific role of this protein is unknown. Researchers suggest that LHFP-like protein 5 is important for the normal function of the inner ear and the hearing process. Hearing requires the conversion of sound waves to nerve impulses that are transmitted via the auditory nerve to the brain. LHFP-like protein 5 may play a role in this conversion process. Studies indicate that this protein may help in the formation of stereocilia, the hairlike structures that project from specialized cells called hair cells. Stereocilia line the inner ear and bend in response to sound waves. This bending motion is critical for converting sound waves to nerve impulses.
How are changes in the LHFPL5 gene related to health conditions?
Where is the LHFPL5 gene located?
Cytogenetic Location: 6p21.31
Molecular Location on chromosome 6: base pairs 35,797,420 to 35,824,075
The LHFPL5 gene is located on the short (p) arm of chromosome 6 at position 21.31.
More precisely, the LHFPL5 gene is located from base pair 35,797,420 to base pair 35,824,075 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about LHFPL5?
You and your healthcare professional may find the following resources about LHFPL5 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the LHFPL5 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding LHFPL5?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (4 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.