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Reviewed March 2013
What is the official name of the INS gene?
The official name of this gene is “insulin.”
INS is the gene's official symbol. The INS gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the INS gene?
The INS gene provides instructions for producing the hormone insulin, which is necessary for the control of glucose levels in the blood. Glucose is a simple sugar and the primary energy source for most cells in the body.
Insulin is produced in a precursor form called proinsulin, which consists of a single chain of protein building blocks (amino acids). The proinsulin chain is cut (cleaved) to form individual pieces called the A and B chains, which are joined together by connections called disulfide bonds to form insulin.
How are changes in the INS gene related to health conditions?
Genetics Home Reference provides information about type 1 diabetes, which is also associated with changes in the INS gene.
Where is the INS gene located?
Cytogenetic Location: 11p15.5
Molecular Location on chromosome 11: base pairs 2,181,008 to 2,182,438
The INS gene is located on the short (p) arm of chromosome 11 at position 15.5.
More precisely, the INS gene is located from base pair 2,181,008 to base pair 2,182,438 on chromosome 11.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about INS?
You and your healthcare professional may find the following resources about INS helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the INS gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding INS?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (12 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.