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Reviewed November 2008
What is the official name of the HSD17B3 gene?
The official name of this gene is “hydroxysteroid (17-beta) dehydrogenase 3.”
HSD17B3 is the gene's official symbol. The HSD17B3 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the HSD17B3 gene?
The HSD17B3 gene provides instructions for making an enzyme called 17-beta hydroxysteroid dehydrogenase 3. This enzyme is active in the male gonads (testes), where it helps to produce the male sex hormone testosterone from a precursor hormone called androstenedione.
Does the HSD17B3 gene share characteristics with other genes?
The HSD17B3 gene belongs to a family of genes called SDR (short chain dehydrogenase/reductase superfamily).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the HSD17B3 gene related to health conditions?
Where is the HSD17B3 gene located?
Cytogenetic Location: 9q22
Molecular Location on chromosome 9: base pairs 96,235,305 to 96,302,301
The HSD17B3 gene is located on the long (q) arm of chromosome 9 at position 22.
More precisely, the HSD17B3 gene is located from base pair 96,235,305 to base pair 96,302,301 on chromosome 9.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about HSD17B3?
You and your healthcare professional may find the following resources about HSD17B3 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the HSD17B3 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding HSD17B3?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.