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Reviewed January 2014
What is the official name of the GYS2 gene?
The official name of this gene is “glycogen synthase 2 (liver).”
GYS2 is the gene's official symbol. The GYS2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the GYS2 gene?
The GYS2 gene provides instructions for making an enzyme called liver glycogen synthase. Liver glycogen synthase is produced solely in liver cells, where it helps form the complex sugar glycogen by linking together molecules of the simple sugar glucose. Glucose that is taken in from food is stored in the body as glycogen, which is a major source of energy. Glycogen that is stored in the liver can be broken down rapidly when glucose is needed to maintain normal blood sugar levels between meals.
Does the GYS2 gene share characteristics with other genes?
The GYS2 gene belongs to a family of genes called glycosyltransferase group 1 domain containing (glycosyltransferase group 1 domain containing).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the GYS2 gene related to health conditions?
Where is the GYS2 gene located?
Cytogenetic Location: 12p12.2
Molecular Location on chromosome 12: base pairs 21,531,527 to 21,630,773
The GYS2 gene is located on the short (p) arm of chromosome 12 at position 12.2.
More precisely, the GYS2 gene is located from base pair 21,531,527 to base pair 21,630,773 on chromosome 12.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about GYS2?
You and your healthcare professional may find the following resources about GYS2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the GYS2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding GYS2?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (6 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.