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Reviewed April 2012
What is the official name of the GSN gene?
The official name of this gene is “gelsolin.”
GSN is the gene's official symbol. The GSN gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the GSN gene?
The GSN gene provides instructions for making two forms of a protein called gelsolin. One form remains inside the cell (cellular gelsolin) and the other form is released from the cell (secreted gelsolin). Both forms of the gelsolin protein attach (bind) to another protein called actin. Actin proteins are organized into filaments, which form a network (the cytoskeleton) that gives structure to cells and allows them to change shape and move. Gelsolin helps assemble or disassemble actin filaments. It is thought that, through this function, the gelsolin protein regulates the formation of the actin cytoskeleton.
How are changes in the GSN gene related to health conditions?
Where is the GSN gene located?
Cytogenetic Location: 9q33
Molecular Location on chromosome 9: base pairs 121,210,803 to 121,332,844
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The GSN gene is located on the long (q) arm of chromosome 9 at position 33.
More precisely, the GSN gene is located from base pair 121,210,803 to base pair 121,332,844 on chromosome 9.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about GSN?
You and your healthcare professional may find the following resources about GSN helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the GSN gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding GSN?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.