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Reviewed February 2012
What is the official name of the GHRHR gene?
The official name of this gene is “growth hormone releasing hormone receptor.”
GHRHR is the gene's official symbol. The GHRHR gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the GHRHR gene?
The GHRHR gene provides instructions for making the growth hormone releasing hormone receptor. This receptor is active (expressed) on the growth-stimulating somatotropic cells in the pituitary gland. This gland is is located at the base of the brain and produces many hormones, including growth hormone. Growth hormone is necessary for the normal growth of the body's bones and tissues. The GHRHR receptor attaches (binds) to a molecule called growth hormone releasing hormone. This binding, along with the actions of other molecules, triggers the production of growth hormone and its release from the pituitary gland.
Does the GHRHR gene share characteristics with other genes?
The GHRHR gene belongs to a family of genes called GPCR (G protein-coupled receptors).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the GHRHR gene related to health conditions?
Where is the GHRHR gene located?
Cytogenetic Location: 7p14
Molecular Location on chromosome 7: base pairs 30,964,021 to 30,979,531
The GHRHR gene is located on the short (p) arm of chromosome 7 at position 14.
More precisely, the GHRHR gene is located from base pair 30,964,021 to base pair 30,979,531 on chromosome 7.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about GHRHR?
You and your healthcare professional may find the following resources about GHRHR helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the GHRHR gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding GHRHR?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (7 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.