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Reviewed March 2013
What is the official name of the GDAP1 gene?
The official name of this gene is “ganglioside induced differentiation associated protein 1.”
GDAP1 is the gene's official symbol. The GDAP1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the GDAP1 gene?
The GDAP1 gene provides instructions for making a protein called ganglioside-induced differentiation-associated protein 1. This protein is found in the outer membrane of mitochondria, the energy-producing centers within cells. Mitochondria are dynamic structures that change shape through processes called fission (splitting into smaller pieces) and fusion (combining pieces). Changes in shape are thought to be critical for mitochondria to work properly. Although the function of the GDAP1 protein is not well understood, it appears to play a role in controlling the shape of mitochondria by promoting fission.
How are changes in the GDAP1 gene related to health conditions?
Where is the GDAP1 gene located?
Cytogenetic Location: 8q21.11
Molecular Location on chromosome 8: base pairs 74,349,251 to 74,367,110
The GDAP1 gene is located on the long (q) arm of chromosome 8 at position 21.11.
More precisely, the GDAP1 gene is located from base pair 74,349,251 to base pair 74,367,110 on chromosome 8.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about GDAP1?
You and your healthcare professional may find the following resources about GDAP1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the GDAP1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding GDAP1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (14 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.