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Reviewed January 2010
What is the official name of the GARS gene?
The official name of this gene is “glycyl-tRNA synthetase.”
GARS is the gene's official symbol. The GARS gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the GARS gene?
The GARS gene provides instructions for making an enzyme called glycyl-tRNA synthetase. This enzyme is found in all cell types and plays an important role in the production (synthesis) of proteins. During protein synthesis, building blocks (amino acids) are connected together in a specific order, creating a chain of amino acids. Glycyl-tRNA synthetase plays a role in adding the amino acid glycine at the proper place in a protein's chain of amino acids.
Does the GARS gene share characteristics with other genes?
The GARS gene belongs to a family of genes called aaRS (aminoacyl tRNA synthetases).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the GARS gene related to health conditions?
Where is the GARS gene located?
Cytogenetic Location: 7p15
Molecular Location on chromosome 7: base pairs 30,594,564 to 30,634,032
The GARS gene is located on the short (p) arm of chromosome 7 at position 15.
More precisely, the GARS gene is located from base pair 30,594,564 to base pair 30,634,032 on chromosome 7.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about GARS?
You and your healthcare professional may find the following resources about GARS helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the GARS gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding GARS?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.