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Reviewed August 2012
What is the official name of the FTL gene?
The official name of this gene is “ferritin, light polypeptide.”
FTL is the gene's official symbol. The FTL gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the FTL gene?
The FTL gene provides instructions for making the ferritin light chain, which is one part (subunit) of a protein called ferritin. Ferritin is made up of 24 subunits formed into a hollow spherical molecule. The 24 subunits consist of varying numbers of the ferritin light chain and another subunit called the ferritin heavy chain, which is produced from another gene. The proportion of the two subunits varies in different tissues.
Ferritin stores and releases iron in cells. Each ferritin molecule can hold as many as 4,500 iron atoms inside its spherical structure. This storage capacity allows ferritin to regulate the amount of iron in cells and tissues. Iron is needed for the body to produce red blood cells.
How are changes in the FTL gene related to health conditions?
Where is the FTL gene located?
Cytogenetic Location: 19q13.33
Molecular Location on chromosome 19: base pairs 48,965,309 to 48,966,879
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The FTL gene is located on the long (q) arm of chromosome 19 at position 13.33.
More precisely, the FTL gene is located from base pair 48,965,309 to base pair 48,966,879 on chromosome 19.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about FTL?
You and your healthcare professional may find the following resources about FTL helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the FTL gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding FTL?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (12 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.