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The official name of this gene is “forkhead box E3.”
FOXE3 is the gene's official symbol. The FOXE3 gene is also known by other names, listed below.
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]
The disease is caused by mutations affecting the gene represented in this entry.
|||107250 (http://omim.org/entry/107250)||ANTERIOR SEGMENT MESENCHYMAL DYSGENESIS|
|||610256 (http://omim.org/entry/610256)||APHAKIA, CONGENITAL PRIMARY|
|601094 (http://omim.org/entry/601094)||FORKHEAD BOX E3|
Cytogenetic Location: 1p32
Molecular Location on chromosome 1: base pairs 47,881,743 to 47,883,723
The FOXE3 gene is located on the short (p) arm of chromosome 1 at position 32.
More precisely, the FOXE3 gene is located from base pair 47,881,743 to base pair 47,883,723 on chromosome 1.
See How do geneticists indicate the location of a gene? (http://ghr.nlm.nih.gov/handbook/howgeneswork/genelocation) in the Handbook.
You and your healthcare professional may find the following resources about FOXE3 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
See How are genetic conditions and genes named? (http://ghr.nlm.nih.gov/handbook/mutationsanddisorders/naming) in the Handbook.
anterior ; congenital ; domain ; dysgenesis ; gene ; protein ; transcription ; transcription factor
You may find definitions for these and many other terms in the Genetics Home Reference Glossary (http://ghr.nlm.nih.gov/glossary).
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? (http://ghr.nlm.nih.gov/handbook/consult/findingprofessional) in the Handbook.