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Reviewed January 2010
What is the official name of the FIG4 gene?
The official name of this gene is “FIG4 phosphoinositide 5-phosphatase.”
FIG4 is the gene's official symbol. The FIG4 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the FIG4 gene?
The FIG4 gene provides instructions for making a protein called Fig4, whose function is not well understood. Researchers believe that the Fig4 protein plays a role in regulating a compound called phosphatidylinositol-3,5-bisphosphate, or PtdIns(3,5)P(2). This compound is involved in the movement of small sac-like structures called vesicles that transport certain substances within cells (vesicle trafficking). The Fig4 protein also seems to help in the survival of nerve cells (neurons).
How are changes in the FIG4 gene related to health conditions?
Genetics Home Reference provides information about amyotrophic lateral sclerosis, which is also associated with changes in the FIG4 gene.
Where is the FIG4 gene located?
Cytogenetic Location: 6q21
Molecular Location on chromosome 6: base pairs 109,691,221 to 109,825,431
The FIG4 gene is located on the long (q) arm of chromosome 6 at position 21.
More precisely, the FIG4 gene is located from base pair 109,691,221 to base pair 109,825,431 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about FIG4?
You and your healthcare professional may find the following resources about FIG4 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the FIG4 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding FIG4?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.