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Reviewed November 2012
What is the official name of the FGF3 gene?
The official name of this gene is “fibroblast growth factor 3.”
FGF3 is the gene's official symbol. The FGF3 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the FGF3 gene?
The FGF3 gene provides instructions for making a protein called fibroblast growth factor 3 (FGF3). This protein is part of a family of proteins called fibroblast growth factors that are involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and development before birth. By attaching to another protein known as a receptor, FGF3 triggers a cascade of chemical reactions inside the cell that signal the cell to undergo certain changes, such as maturing to take on specialized functions. During development before birth, the signals triggered by the FGF3 protein stimulate cells to form the structures that make up the inner ears. The FGF3 protein is also involved in the development of many other organs and structures, including the outer ears and teeth.
How are changes in the FGF3 gene related to health conditions?
Where is the FGF3 gene located?
Cytogenetic Location: 11q13
Molecular Location on chromosome 11: base pairs 69,809,968 to 69,819,424
The FGF3 gene is located on the long (q) arm of chromosome 11 at position 13.
More precisely, the FGF3 gene is located from base pair 69,809,968 to base pair 69,819,424 on chromosome 11.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about FGF3?
You and your healthcare professional may find the following resources about FGF3 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the FGF3 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding FGF3?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (6 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.