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Reviewed July 2014
What is the official name of the FAS gene?
The official name of this gene is “Fas cell surface death receptor.”
FAS is the gene's official symbol. The FAS gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the FAS gene?
The FAS gene provides instructions for making a protein that is involved in signaling. Three FAS proteins group together to form a structure called a trimer, which then interacts with other molecules to perform its signaling function. This signaling initiates a process called a caspase cascade. The caspase cascade is a series of steps that results in the self-destruction of cells (apoptosis) when they are not needed.
Does the FAS gene share characteristics with other genes?
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the FAS gene related to health conditions?
Where is the FAS gene located?
Cytogenetic Location: 10q24.1
Molecular Location on chromosome 10: base pairs 88,969,800 to 89,017,058
The FAS gene is located on the long (q) arm of chromosome 10 at position 24.1.
More precisely, the FAS gene is located from base pair 88,969,800 to base pair 89,017,058 on chromosome 10.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about FAS?
You and your healthcare professional may find the following resources about FAS helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the FAS gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding FAS?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (15 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.