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FAM161A

FAM161A

The information on this page was automatically extracted from online scientific databases.

What is the official name of the FAM161A gene?

The official name of this gene is “family with sequence similarity 161, member A.”

FAM161A is the gene's official symbol. The FAM161A gene is also known by other names, listed below.

Read more about gene names and symbols on the About page.

What is the normal function of the FAM161A gene?

From NCBI GeneThis link leads to a site outside Genetics Home Reference.:

This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.[provided by RefSeq, Jan 2011]

From UniProtThis link leads to a site outside Genetics Home Reference.:

Involved in ciliogenesis.

How are changes in the FAM161A gene related to health conditions?

Genetics Home Reference provides information about retinitis pigmentosa, which is associated with changes in the FAM161A gene.
UniProtThis link leads to a site outside Genetics Home Reference. provides the following information about the FAM161A gene's known or predicted involvement in human disease.

Retinitis pigmentosa 28 (RP28): A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. The disease is caused by mutations affecting the gene represented in this entry.

NCBI GeneThis link leads to a site outside Genetics Home Reference. lists the following diseases or traits (phenotypes) known or believed to be associated with changes in the FAM161A gene.
  • Retinitis pigmentosa 28
OMIM.orgThis link leads to a site outside Genetics Home Reference., a catalog designed for genetics professionals and researchers, provides the following information about the FAM161A gene and its association with health conditions.
OMIM
Number
Title

Where is the FAM161A gene located?

Cytogenetic Location: 2p15

Molecular Location on chromosome 2: base pairs 61,824,847 to 61,854,142

The FAM161A gene is located on the short (p) arm of chromosome 2 at position 15.

The FAM161A gene is located on the short (p) arm of chromosome 2 at position 15.

More precisely, the FAM161A gene is located from base pair 61,824,847 to base pair 61,854,142 on chromosome 2.

See How do geneticists indicate the location of a gene? in the Handbook.

Where can I find additional information about FAM161A?

You and your healthcare professional may find the following resources about FAM161A helpful.

You may also be interested in these resources, which are designed for genetics professionals and researchers.

What other names do people use for the FAM161A gene or gene products?

Where can I find general information about genes?

The Handbook provides basic information about genetics in clear language.

These links provide additional genetics resources that may be useful.

What glossary definitions help with understanding FAM161A?

autosomal ; autosomal recessive ; expressed ; fundus ; gene ; peripheral ; photoreceptor ; pigment ; recessive ; retina ; transcript

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.

 

The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

 
Published: February 23, 2015