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Reviewed February 2013
What is the official name of the ETV6 gene?
The official name of this gene is “ets variant 6.”
ETV6 is the gene's official symbol. The ETV6 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ETV6 gene?
The ETV6 gene provides instructions for producing a protein that functions as a transcription factor, which means that it attaches (binds) to specific regions of DNA and controls the activity of certain genes. The ETV6 protein is found in the nucleus of cells throughout the body, where it turns off (represses) gene activity. It plays a key role in development before birth and in regulating blood cell formation.
How are changes in the ETV6 gene related to health conditions?
Where is the ETV6 gene located?
Cytogenetic Location: 12p13
Molecular Location on chromosome 12: base pairs 11,649,854 to 11,895,402
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The ETV6 gene is located on the short (p) arm of chromosome 12 at position 13.
More precisely, the ETV6 gene is located from base pair 11,649,854 to base pair 11,895,402 on chromosome 12.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ETV6?
You and your healthcare professional may find the following resources about ETV6 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ETV6 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ETV6?
acute ; acute lymphoblastic leukemia ; acute myeloid leukemia ; AML ; bone marrow ; cancer ; cell ; chronic ; DNA ; eosinophils ; fusion gene ; gene ; inherited ; leukemia ; mast cells ; mutation ; myelodysplastic syndrome ; myeloid ; neutrophils ; nucleus ; oncogene ; population ; proliferation ; protein ; rearrangement ; somatic mutation ; syndrome ; transcription ; transcription factor ; translocation ; white blood cells
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.