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Reviewed May 2010
What is the official name of the DRD5 gene?
The official name of this gene is “dopamine receptor D5.”
DRD5 is the gene's official symbol. The DRD5 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the DRD5 gene?
The DRD5 gene provides instructions for making a protein called dopamine receptor D5, which is found in the brain. This protein works together with a chemical messenger (neurotransmitter) called dopamine. Dopamine fits into the D5 receptor like a key in a lock, which triggers chemical reactions within nerve cells. Dopamine signaling has many critical functions in the brain, including regulation of attention, mood, memory, learning, and movement.
Does the DRD5 gene share characteristics with other genes?
The DRD5 gene belongs to a family of genes called GPCR (G protein-coupled receptors).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the DRD5 gene related to health conditions?
Where is the DRD5 gene located?
Cytogenetic Location: 4p16.1
Molecular Location on chromosome 4: base pairs 9,781,634 to 9,784,009
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The DRD5 gene is located on the short (p) arm of chromosome 4 at position 16.1.
More precisely, the DRD5 gene is located from base pair 9,781,634 to base pair 9,784,009 on chromosome 4.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about DRD5?
You and your healthcare professional may find the following resources about DRD5 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the DRD5 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding DRD5?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.