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Reviewed January 2014
What is the official name of the CYP1B1 gene?
The official name of this gene is “cytochrome P450, family 1, subfamily B, polypeptide 1.”
CYP1B1 is the gene's official symbol. The CYP1B1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the CYP1B1 gene?
The CYP1B1 gene provides instructions for producing an enzyme that is a member of the cytochrome P450 family of enzymes. These enzymes are involved in many processes in the body, such as assisting with reactions that break down drugs and produce certain fats (lipids). The CYP1B1 enzyme participates in biochemical reactions in which an oxygen atom is added to other molecules.
The CYP1B1 enzyme is active in many tissues, including structures of the eye. The function of the CYP1B1 enzyme in the development of the eye is unclear, but it may play a role in forming structures at the front of the eye and may also be involved in a process that regulates the secretion of fluid inside the eye.
Does the CYP1B1 gene share characteristics with other genes?
The CYP1B1 gene belongs to a family of genes called CYP (cytochrome P450s).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the CYP1B1 gene related to health conditions?
Where is the CYP1B1 gene located?
Cytogenetic Location: 2p22.2
Molecular Location on chromosome 2: base pairs 38,067,602 to 38,076,180
The CYP1B1 gene is located on the short (p) arm of chromosome 2 at position 22.2.
More precisely, the CYP1B1 gene is located from base pair 38,067,602 to base pair 38,076,180 on chromosome 2.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about CYP1B1?
You and your healthcare professional may find the following resources about CYP1B1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the CYP1B1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding CYP1B1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (14 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.