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Reviewed April 2012
What is the official name of the CISD2 gene?
The official name of this gene is “CDGSH iron sulfur domain 2.”
CISD2 is the gene's official symbol. The CISD2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the CISD2 gene?
The CISD2 gene provides instructions for making a protein that is found in the outer membrane of cell structures called mitochondria. Mitochondria are involved in a wide variety of cellular activities, including energy production, chemical signaling, and regulation of cell growth and division. The exact function of the CISD2 protein is unknown, but it is thought to help keep mitochondria functioning normally.
How are changes in the CISD2 gene related to health conditions?
Where is the CISD2 gene located?
Cytogenetic Location: 4q24
Molecular Location on chromosome 4: base pairs 102,868,978 to 102,892,807
The CISD2 gene is located on the long (q) arm of chromosome 4 at position 24.
More precisely, the CISD2 gene is located from base pair 102,868,978 to base pair 102,892,807 on chromosome 4.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about CISD2?
You and your healthcare professional may find the following resources about CISD2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the CISD2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding CISD2?
amino acid ; atrophy ; autophagy ; cell ; diabetes ; diabetes mellitus ; domain ; endoplasmic reticulum ; gastrointestinal ; gene ; glutamic acid ; glutamine ; injury ; insulin ; iron ; mitochondria ; mutation ; optic atrophy ; protein ; syndrome
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.