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CHD1L

CHD1L

The information on this page was automatically extracted from online scientific databases.

What is the official name of the CHD1L gene?

The official name of this gene is “chromodomain helicase DNA binding protein 1-like.”

CHD1L is the gene's official symbol. The CHD1L gene is also known by other names, listed below.

Read more about gene names and symbols on the About page.

What is the normal function of the CHD1L gene?

From NCBI GeneThis link leads to a site outside Genetics Home Reference.:

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]

From UniProtThis link leads to a site outside Genetics Home Reference.:

DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.

How are changes in the CHD1L gene related to health conditions?

Genetics Home Reference provides information about 1q21.1 microdeletion, which is associated with changes in the CHD1L gene.
UniProt and NCBI Gene cite these articles in OMIM, a catalog designed for genetics professionals and researchers that provides detailed information about genetic conditions and genes.
 Article
Number
Main Topic

Where is the CHD1L gene located?

Cytogenetic Location: 1q12

Molecular Location on chromosome 1: base pairs 147,172,803 to 147,295,765

The CHD1L gene is located on the long (q) arm of chromosome 1 at position 12.

The CHD1L gene is located on the long (q) arm of chromosome 1 at position 12.

More precisely, the CHD1L gene is located from base pair 147,172,803 to base pair 147,295,765 on chromosome 1.

See How do geneticists indicate the location of a gene? in the Handbook.

Where can I find additional information about CHD1L?

You may also be interested in these resources, which are designed for genetics professionals and researchers.

What other names do people use for the CHD1L gene or gene products?

  • ALC1
  • CHDL

Where can I find general information about genes?

The Handbook provides basic information about genetics in clear language.

These links provide additional genetics resources that may be useful.

What glossary definitions help with understanding CHD1L?

ADP ; ATP ; chromatin ; DNA ; DNA damage ; DNA repair ; gene ; helicase ; nucleosome ; protein

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.

 

The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

 
Published: September 15, 2014