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Reviewed January 2014
What is the official name of the CEBPA gene?
The official name of this gene is “CCAAT/enhancer binding protein alpha.”
CEBPA is the gene's official symbol. The CEBPA gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the CEBPA gene?
The CEBPA gene provides instructions for making a protein called CCAAT/enhancer-binding protein alpha. This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity (expression) of certain genes. CCAAT/enhancer-binding protein alpha is involved in the maturation (differentiation) of certain blood cells. It is also believed to act as a tumor suppressor, which means that it is involved in cellular mechanisms that help prevent the cells from growing and dividing too rapidly or in an uncontrolled way.
Does the CEBPA gene share characteristics with other genes?
The CEBPA gene belongs to a family of genes called bZIP (basic leucine zipper proteins).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the CEBPA gene related to health conditions?
Where is the CEBPA gene located?
Cytogenetic Location: 19q13.1
Molecular Location on chromosome 19: base pairs 33,299,934 to 33,302,564
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The CEBPA gene is located on the long (q) arm of chromosome 19 at position 13.1.
More precisely, the CEBPA gene is located from base pair 33,299,934 to base pair 33,302,564 on chromosome 19.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about CEBPA?
You and your healthcare professional may find the following resources about CEBPA helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the CEBPA gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding CEBPA?
acute ; acute myeloid leukemia ; AML ; cancer ; cell ; differentiation ; DNA ; enhancer ; familial ; gene ; gene expression ; inherited ; leukemia ; mutation ; myeloid ; protein ; somatic mutation ; sporadic ; transcription ; transcription factor ; tumor ; white blood cells
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.