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The information on this page was automatically extracted from online scientific databases.

What is the official name of the CCR6 gene?

The official name of this gene is “chemokine (C-C motif) receptor 6.”

CCR6 is the gene's official symbol. The CCR6 gene is also known by other names, listed below.

Read more about gene names and symbols on the About page.

What is the normal function of the CCR6 gene?

From NCBI GeneThis link leads to a site outside Genetics Home Reference.:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

From UniProt (CCR6_HUMAN)This link leads to a site outside Genetics Home Reference.:

Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

NOTE: UniProt (CCR6_HUMAN)This link leads to a site outside Genetics Home Reference. suggests using caution when interpreting this information.

How are changes in the CCR6 gene related to health conditions?

Genetics Home Reference provides information about rheumatoid arthritis, which is associated with changes in the CCR6 gene.
OMIM.orgThis link leads to a site outside Genetics Home Reference., a catalog designed for genetics professionals and researchers, provides the following information about the CCR6 gene and its association with health conditions.

Where is the CCR6 gene located?

Cytogenetic Location: 6q27

Molecular Location on chromosome 6: base pairs 167,111,807 to 167,139,141

(Homo sapiens Annotation Release 107, GRCh38.p2) (NCBIThis link leads to a site outside Genetics Home Reference.)

The CCR6 gene is located on the long (q) arm of chromosome 6 at position 27.

The CCR6 gene is located on the long (q) arm of chromosome 6 at position 27.

More precisely, the CCR6 gene is located from base pair 167,111,807 to base pair 167,139,141 on chromosome 6.

See How do geneticists indicate the location of a gene? in the Handbook.

Where can I find additional information about CCR6?

You may also be interested in these resources, which are designed for genetics professionals and researchers.

What other names do people use for the CCR6 gene or gene products?

  • BN-1
  • CC-CKR-6
  • C-C CKR-6
  • CCR-6
  • CD196
  • CKRL3
  • CKR-L3
  • CMKBR6
  • DCR2
  • DRY6
  • GPR29
  • GPRCY4
  • STRL22

Where can I find general information about genes?

The Handbook provides basic information about genetics in clear language.

These links provide additional genetics resources that may be useful.

What glossary definitions help with understanding CCR6?

calcium ; cell ; differentiation ; expressed ; gene ; intracellular ; ions ; ligand ; lineage ; macrophage ; Met ; protein ; receptor ; transcript ; transmembrane

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.


The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

Published: February 1, 2016