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Reviewed June 2014
What is the official name of the AUH gene?
The official name of this gene is “AU RNA binding protein/enoyl-CoA hydratase.”
AUH is the gene's official symbol. The AUH gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the AUH gene?
The AUH gene provides instructions for producing an enzyme called 3-methylglutaconyl-CoA hydratase. This enzyme is found in cell structures called mitochondria, which convert energy from food into a form that cells can use. Within mitochondria, this enzyme plays an important role in breaking down proteins into smaller molecules that cells can use to produce energy. Specifically, 3-methylglutaconyl-CoA hydratase is responsible for the fifth step in breaking down the protein building block (amino acid) leucine. The enzyme converts a molecule called 3-methylglutaconyl-CoA into another molecule called 3-hydroxy-3-methylglutaryl-CoA.
3-methylglutaconyl-CoA hydratase also has the ability to attach (bind) to RNA, a chemical cousin of DNA. Researchers are working to determine the purpose of this RNA-binding ability.
How are changes in the AUH gene related to health conditions?
Where is the AUH gene located?
Cytogenetic Location: 9q22.31
Molecular Location on chromosome 9: base pairs 91,213,814 to 91,361,938
The AUH gene is located on the long (q) arm of chromosome 9 at position 22.31.
More precisely, the AUH gene is located from base pair 91,213,814 to base pair 91,361,938 on chromosome 9.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about AUH?
You and your healthcare professional may find the following resources about AUH helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the AUH gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding AUH?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (7 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.