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Reviewed January 2008
What is the official name of the ATL1 gene?
The official name of this gene is “atlastin GTPase 1.”
ATL1 is the gene's official symbol. The ATL1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ATL1 gene?
The ATL1 gene provides instructions for producing a protein called atlastin-1. Atlastin-1 is found throughout the body, particularly in the brain. In cells, this protein is found in structures known as the endoplasmic reticulum and the Golgi apparatus, which are involved in the movement of proteins and cell components within the cell. Atlastin-1 likely plays a role in the transportation of cell components and in the formation of the endoplasmic reticulum and Golgi apparatus, each of which is involved in the growth of axons (specialized extensions of nerve cells that transmit nerve impulses). Atlastin-1 is necessary for the formation and growth of axons; however, its precise function remains unclear.
How are changes in the ATL1 gene related to health conditions?
Where is the ATL1 gene located?
Cytogenetic Location: 14q22.1
Molecular Location on chromosome 14: base pairs 50,533,081 to 50,633,067
The ATL1 gene is located on the long (q) arm of chromosome 14 at position 22.1.
More precisely, the ATL1 gene is located from base pair 50,533,081 to base pair 50,633,067 on chromosome 14.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ATL1?
You and your healthcare professional may find the following resources about ATL1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ATL1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ATL1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (5 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.