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Reviewed May 2014
What is the official name of the ALG6 gene?
The official name of this gene is “ALG6, alpha-1,3-glucosyltransferase.”
ALG6 is the gene's official symbol. The ALG6 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ALG6 gene?
The ALG6 gene provides instructions for making an enzyme that is involved in a process called glycosylation. Glycosylation is a process by which sugar molecules (oligosaccharides) are attached to proteins and fats. Oligosaccharides are made up of many sugar molecules that are attached to one another in a stepwise process forming a complex chain. Glycosylation modifies proteins so they can perform a wider variety of functions. The enzyme produced from the ALG6 gene transfers a simple sugar called glucose to the growing oligosaccharide. Once the correct number of sugar molecules are linked together, the oligosaccharide is attached to a protein or fat.
How are changes in the ALG6 gene related to health conditions?
Where is the ALG6 gene located?
Cytogenetic Location: 1p31.3
Molecular Location on chromosome 1: base pairs 63,367,590 to 63,438,562
The ALG6 gene is located on the short (p) arm of chromosome 1 at position 31.3.
More precisely, the ALG6 gene is located from base pair 63,367,590 to base pair 63,438,562 on chromosome 1.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ALG6?
You and your healthcare professional may find the following resources about ALG6 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ALG6 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ALG6?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (6 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.