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Reviewed November 2009
What is the official name of the ACADVL gene?
The official name of this gene is “acyl-CoA dehydrogenase, very long chain.”
ACADVL is the gene's official symbol. The ACADVL gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ACADVL gene?
The ACADVL gene provides instructions for making an enzyme called very long-chain acyl-CoA dehydrogenase (VLCAD). This enzyme functions within mitochondria, the energy-producing centers in cells. Very long-chain acyl-CoA dehydrogenase is essential for fatty acid oxidation, which is the multistep process that breaks down (metabolizes) fats and converts them to energy.
Very long-chain acyl-CoA dehydrogenase is required to metabolize a group of fats called very long-chain fatty acids. These fatty acids are found in food and body fat. Fatty acids are a major source of energy for the heart and muscles. During periods without food (fasting), fatty acids are also an important energy source for the liver and other tissues.
How are changes in the ACADVL gene related to health conditions?
Where is the ACADVL gene located?
Cytogenetic Location: 17p13.1
Molecular Location on chromosome 17: base pairs 7,217,124 to 7,225,266
The ACADVL gene is located on the short (p) arm of chromosome 17 at position 13.1.
More precisely, the ACADVL gene is located from base pair 7,217,124 to base pair 7,225,266 on chromosome 17.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ACADVL?
You and your healthcare professional may find the following resources about ACADVL helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ACADVL gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ACADVL?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.