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- D2HGDH: D-2-hydroxyglutarate dehydrogenase
- DBT: dihydrolipoamide branched chain transacylase E2
- DCTN1: dynactin 1 (p150, glued homolog, Drosophila)
- DCX: doublecortex; lissencephaly, X-linked (doublecortin)
- DDC: dopa decarboxylase (aromatic L-amino acid decarboxylase)
- DFNA5: deafness, autosomal dominant 5
- DFNB31: deafness, autosomal recessive 31
- DFNB59: deafness, autosomal recessive 59
- DHCR7: 7-dehydrocholesterol reductase
- DIRAS3: DIRAS family, GTP-binding RAS-like 3
- DLD: dihydrolipoamide dehydrogenase
- DMD: dystrophin (muscular dystrophy, Duchenne and Becker types)
- DMPK: dystrophia myotonica-protein kinase
- DNAJC19: DnaJ (Hsp40) homolog, subfamily C, member 19
- DNM2: dynamin 2
- DRD3: dopamine receptor D3
- DSPP: dentin sialophosphoprotein
- DUOX2: dual oxidase 2
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