Negative regulation of cellular process

Negative regulation of cellular process

• ACVR1: activin A receptor, type I
• ACVRL1: activin A receptor type II-like 1
• ADA: adenosine deaminase
• ANG: angiogenin, ribonuclease, RNase A family, 5
• APC: adenomatous polyposis coli
• APOE: apolipoprotein E
• ATM: ataxia telangiectasia mutated
• BARD1: BRCA1 associated RING domain 1
• BCOR: BCL6 co-repressor
• BLM: Bloom syndrome, RecQ helicase-like
• BRAF: v-raf murine sarcoma viral oncogene homolog B1
• BRCA1: breast cancer 1, early onset
• BRCA2: breast cancer 2, early onset
• CD40LG: CD40 ligand
• CDKN1C: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
• CLN3: ceroid-lipofuscinosis, neuronal 3
• COL4A3: collagen, type IV, alpha 3 (Goodpasture antigen)
• DRD3: dopamine receptor D3
• EIF2B3: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
• EIF2B4: eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
• EIF2B5: eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
• ENG: endoglin
• FOXP3: forkhead box P3
• G6PD: glucose-6-phosphate dehydrogenase
• GLA: galactosidase, alpha
• GPR98: G protein-coupled receptor 98
• HSPB1: heat shock 27kDa protein 1
• IL1A: interleukin 1, alpha
• LEPRE1: leucine proline-enriched proteoglycan (leprecan) 1
• MECP2: methyl CpG binding protein 2 (Rett syndrome)
• MEN1: multiple endocrine neoplasia I
• MFN2: mitofusin 2
• NF1: neurofibromin 1
• NF2: neurofibromin 2 (merlin)
• NLRP12: NLR family, pyrin domain containing 12
• NOTCH2: Notch homolog 2 (Drosophila)
• NR0B1: nuclear receptor subfamily 0, group B, member 1
• NSD1: nuclear receptor binding SET domain protein 1
• OPA1: optic atrophy 1 (autosomal dominant)
• PKHD1: polycystic kidney and hepatic disease 1 (autosomal recessive)
• PROC: protein C (inactivator of coagulation factors Va and VIIIa)
• PROK2: prokineticin 2
• PSEN1: presenilin 1
• PTEN: phosphatase and tensin homolog
• RB1: retinoblastoma 1
• RUNX2: runt-related transcription factor 2
• SBDS: Shwachman-Bodian-Diamond syndrome
• SERPING1: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• SMAD4: SMAD family member 4
• SNAI2: snail homolog 2 (Drosophila)
• SNCA: synuclein, alpha (non A4 component of amyloid precursor)
• SOD1: superoxide dismutase 1, soluble
• SOST: sclerosteosis
• STAT3: signal transducer and activator of transcription 3 (acute-phase response factor)
• STK11: serine/threonine kinase 11
• TBX5: T-box 5
• TGFB1: transforming growth factor, beta 1
• TP53: tumor protein p53
• TRIOBP: TRIO and F-actin binding protein
• TSC1: tuberous sclerosis 1
• TSC2: tuberous sclerosis 2
• TWIST1: twist homolog 1 (Drosophila)
• USH2A: Usher syndrome 2A (autosomal recessive, mild)
• VHL: von Hippel-Lindau tumor suppressor
• WFS1: Wolfram syndrome 1 (wolframin)
• WT1: Wilms tumor 1
• ZEB2: zinc finger E-box binding homeobox 2

Source: Gene Ontology Consortium (June 2009).