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Protein complex

Protein complex

  • ACTA2: actin, alpha 2, smooth muscle, aorta
  • ACTB: actin, beta
  • ALK: anaplastic lymphoma receptor tyrosine kinase
  • ALS2: amyotrophic lateral sclerosis 2 (juvenile)
  • AR: androgen receptor
  • BRCA1: breast cancer 1, early onset
  • BRCA2: breast cancer 2, early onset
  • BSND: barttin CLCNK-type chloride channel accessory beta subunit
  • CAPN3: calpain 3, (p94)
  • CEP290: centrosomal protein 290kDa
  • CFTR: cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • CISD2: CDGSH iron sulfur domain 2
  • COL6A1: collagen, type VI, alpha 1
  • COL6A2: collagen, type VI, alpha 2
  • CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
  • DMD: dystrophin
  • DNAJC19: DnaJ (Hsp40) homolog, subfamily C, member 19
  • ERCC8: excision repair cross-complementation group 8
  • FOXP3: forkhead box P3
  • GCH1: GTP cyclohydrolase 1
  • HTT: huntingtin
  • MEN1: multiple endocrine neoplasia I
  • MITF: microphthalmia-associated transcription factor
  • MYH9: myosin, heavy chain 9, non-muscle
  • MYO5B: myosin VB
  • NOD2: nucleotide-binding oligomerization domain containing 2
  • NTRK1: neurotrophic tyrosine kinase, receptor, type 1
  • OTX2: orthodenticle homeobox 2
  • PAX2: paired box 2
  • PRKAR1A: protein kinase, cAMP-dependent, regulatory, type I, alpha
  • PSEN2: presenilin 2
  • RYR2: ryanodine receptor 2 (cardiac)
  • SKI: SKI proto-oncogene
  • SMARCA4: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • SMARCB1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  • SMARCE1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • SOD1: superoxide dismutase 1, soluble
  • SOX9: SRY (sex determining region Y)-box 9
  • SRCAP: Snf2-related CREBBP activator protein
  • TP53: tumor protein p53
  • TSC1: tuberous sclerosis 1
  • 3M complex
  • Actin filament
  • Angiogenin-PRI complex
    • ANG: angiogenin, ribonuclease, RNase A family, 5
  • AP-type membrane coat adaptor complex
    • LDLRAP1: low density lipoprotein receptor adaptor protein 1
  • Aster
    • PAFAH1B1: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
  • ATP-binding cassette (ABC) transporter complex
    • ABCG5: ATP-binding cassette, sub-family G (WHITE), member 5
    • ABCG8: ATP-binding cassette, sub-family G (WHITE), member 8
  • BBSome
    • BBS1: Bardet-Biedl syndrome 1
  • Beta-catenin destruction complex
    • APC: adenomatous polyposis coli
    • CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
  • BLOC complex
    • HPS1: Hermansky-Pudlak syndrome 1
    • HPS3: Hermansky-Pudlak syndrome 3
  • BRCA1-A complex
    • BARD1: BRCA1 associated RING domain 1
    • BRCA1: breast cancer 1, early onset
  • BRCA2-MAGE-D1 complex
    • BRCA2: breast cancer 2, early onset
  • Carboxy-terminal domain protein kinase complex
    • ERCC2: excision repair cross-complementation group 2
    • ERCC3: excision repair cross-complementation group 3
  • Catalytic complex
  • Catenin complex
    • APC: adenomatous polyposis coli
    • CDH1: cadherin 1, type 1, E-cadherin (epithelial)
    • CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
  • Catenin-TCF7L2 complex
    • CTNNB1: catenin (cadherin-associated protein), beta 1, 88kDa
  • CNTFR-CLCF1 complex
    • CLCF1: cardiotrophin-like cytokine factor 1
  • Cohesin complex
    • SMC1A: structural maintenance of chromosomes 1A
    • SMC3: structural maintenance of chromosomes 3
  • Cohesin core heterodimer
    • SMC1A: structural maintenance of chromosomes 1A
  • Collagen trimer
  • Complex of collagen trimers
  • Connexon complex
    • GJA1: gap junction protein, alpha 1, 43kDa
    • GJB1: gap junction protein, beta 1, 32kDa
    • GJB2: gap junction protein, beta 2, 26kDa
  • COP9 signalosome
    • MYH9: myosin, heavy chain 9, non-muscle
    • NOD2: nucleotide-binding oligomerization domain containing 2
  • CRLF-CLCF1 complex
    • CLCF1: cardiotrophin-like cytokine factor 1
    • CRLF1: cytokine receptor-like factor 1
  • CSF1-CSF1R complex
    • CSF1R: colony stimulating factor 1 receptor
  • Cyclin-dependent protein kinase holoenzyme complex
    • ERCC2: excision repair cross-complementation group 2
  • Cytochrome complex
    • BCS1L: BC1 (ubiquinol-cytochrome c reductase) synthesis-like
    • MT-CYB: mitochondrially encoded cytochrome b
  • Death-inducing signaling complex
    • FAS: Fas cell surface death receptor
  • DNA bending complex
    • KAT6B: K(lysine) acetyltransferase 6B
  • DNA packaging complex
    • KAT6B: K(lysine) acetyltransferase 6B
  • DNA repair complex
  • DNA replication factor A complex
    • SMARCAL1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
    • XPA: xeroderma pigmentosum, complementation group A
  • Dystroglycan complex
    • SGCB: sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
    • SGCD: sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    • SGCE: sarcoglycan, epsilon
    • SGCG: sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
  • Dystrophin-associated glycoprotein complex
  • Elongator holoenzyme complex
    • IKBKAP: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • Endopeptidase Clp complex
    • CLPP: caseinolytic mitochondrial matrix peptidase proteolytic subunit
  • Endoplasmic reticulum Sec complex
    • CFTR: cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • ESCRT complex
    • CHMP2B: charged multivesicular body protein 2B
  • Eukaryotic translation initiation factor 2B complex
    • EIF2B1: eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
    • EIF2B2: eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
    • EIF2B3: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
    • EIF2B4: eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
    • EIF2B5: eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
  • Exon-exon junction complex
    • RBM8A: RNA binding motif protein 8A
  • Exosome (RNase complex)
  • Fanconi anaemia nuclear complex
    • FANCA: Fanconi anemia, complementation group A
    • FANCC: Fanconi anemia, complementation group C
    • FANCG: Fanconi anemia, complementation group G
  • Ferritin complex
    • FTL: ferritin, light polypeptide
  • Fibrinogen complex
    • FGA: fibrinogen alpha chain
    • FGB: fibrinogen beta chain
    • FGG: fibrinogen gamma chain
    • FN1: fibronectin 1
  • Filamentous actin
    • ESPN: espin
    • MYO1A: myosin IA
    • MYO6: myosin VI
    • PKD2: polycystic kidney disease 2 (autosomal dominant)
  • Fumarate reductase complex
    • SDHA: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    • SDHB: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
    • SDHC: succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
    • SDHD: succinate dehydrogenase complex, subunit D, integral membrane protein
  • Gamma-secretase complex
    • PSEN1: presenilin 1
    • PSENEN: presenilin enhancer gamma secretase subunit
  • Gamma-tubulin complex
    • BRCA1: breast cancer 1, early onset
    • CEP290: centrosomal protein 290kDa
  • Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
    • PIGA: phosphatidylinositol glycan anchor biosynthesis, class A
  • Golgi transport complex
    • COG5: component of oligomeric golgi complex 5
  • Haptoglobin-hemoglobin complex
    • HBA2: hemoglobin, alpha 2
    • HBB: hemoglobin, beta
  • Hemoglobin complex
    • HBA2: hemoglobin, alpha 2
    • HBB: hemoglobin, beta
  • Heterotrimeric G-protein complex
    • GNA11: guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
    • GNAI3: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
    • GNAS: GNAS complex locus
    • GNAT1: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
    • GNAT2: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
  • I-kappaB/NF-kappaB complex
    • NFKBIA: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • Integrin complex
    • ITGB2: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    • ITGB4: integrin, beta 4
    • MYH9: myosin, heavy chain 9, non-muscle
  • Intermediate filament
  • Intraciliary transport particle
    • IFT122: intraflagellar transport 122
    • IFT140: intraflagellar transport 140
    • IFT43: intraflagellar transport 43
    • IFT80: intraflagellar transport 80
    • WDR19: WD repeat domain 19
    • WDR35: WD repeat domain 35
  • Intraciliary transport particle A
    • IFT122: intraflagellar transport 122
    • IFT140: intraflagellar transport 140
    • IFT43: intraflagellar transport 43
    • WDR19: WD repeat domain 19
    • WDR35: WD repeat domain 35
  • Intraciliary transport particle B
    • IFT80: intraflagellar transport 80
  • Kinetochore
    • APC: adenomatous polyposis coli
    • DCTN1: dynactin 1
    • PAFAH1B1: platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
    • PSEN1: presenilin 1
    • PSEN2: presenilin 2
    • SMC1A: structural maintenance of chromosomes 1A
  • LINC complex
    • SYNE1: spectrin repeat containing, nuclear envelope 1
  • MAML1-RBP-Jkappa- ICN1 complex
    • NOTCH1: notch 1
    • RBPJ: recombination signal binding protein for immunoglobulin kappa J region
  • MCM complex
    • MCM6: minichromosome maintenance complex component 6
  • Mediator complex
    • GLI3: GLI family zinc finger 3
    • MED12: mediator complex subunit 12
  • Membrane coat
    • LDLRAP1: low density lipoprotein receptor adaptor protein 1
  • MHC class I peptide loading complex
    • CALR: calreticulin
  • MHC protein complex
    • HLA-B: major histocompatibility complex, class I, B
    • HLA-DPB1: major histocompatibility complex, class II, DP beta 1
    • HLA-DQA1: major histocompatibility complex, class II, DQ alpha 1
    • HLA-DQB1: major histocompatibility complex, class II, DQ beta 1
    • HLA-DRB1: major histocompatibility complex, class II, DR beta 1
  • Microtubule
  • Microtubule associated complex
  • Mismatch repair complex
    • MLH1: mutL homolog 1
    • MSH2: mutS homolog 2
    • MSH6: mutS homolog 6
    • PMS2: PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
    • WRN: Werner syndrome, RecQ helicase-like
  • MMXD complex
    • ERCC2: excision repair cross-complementation group 2
  • Molybdopterin synthase complex
    • MOCS2: molybdenum cofactor synthesis 2
  • Mre11 complex
    • NBN: nibrin
    • RAD50: RAD50 homolog (S. cerevisiae)
  • Myb complex
    • FLNA: filamin A, alpha
  • Myosin complex
  • NLRP1 inflammasome complex
    • NLRP1: NLR family, pyrin domain containing 1
  • NLRP3 inflammasome complex
    • NLRP3: NLR family, pyrin domain containing 3
  • Nuclear RNA export factor complex
  • Nucleotide-excision repair complex
    • ERCC8: excision repair cross-complementation group 8
    • XPC: xeroderma pigmentosum, complementation group C
  • Origin recognition complex
    • ORC1: origin recognition complex, subunit 1
    • ORC4: origin recognition complex, subunit 4
    • ORC6: origin recognition complex, subunit 6
  • Palmitoyltransferase complex
    • SPTLC1: serine palmitoyltransferase, long chain base subunit 1
  • Paraferritin complex
    • SLC11A2: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
  • PcG protein complex
    • BCOR: BCL6 corepressor
    • EZH2: enhancer of zeste 2 polycomb repressive complex 2 subunit
  • PCSK9-AnxA2 complex
    • PCSK9: proprotein convertase subtilisin/kexin type 9
  • PCSK9-LDLR complex
    • PCSK9: proprotein convertase subtilisin/kexin type 9
  • Podosome
    • GSN: gelsolin
  • Polycystin complex
    • PKD1: polycystic kidney disease 1 (autosomal dominant)
    • PKD2: polycystic kidney disease 2 (autosomal dominant)
  • Pore complex
    • AAAS: achalasia, adrenocortical insufficiency, alacrimia
  • Proteasome complex
    • HSPB1: heat shock 27kDa protein 1
    • PSMB8: proteasome (prosome, macropain) subunit, beta type, 8
    • VCP: valosin containing protein
  • Proteasome core complex
    • PSMB8: proteasome (prosome, macropain) subunit, beta type, 8
  • Protein complex involved in cell adhesion
    • ITGB2: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
    • ITGB4: integrin, beta 4
    • MYH9: myosin, heavy chain 9, non-muscle
  • Proton-transporting two-sector ATPase complex
    • ATP6V0A2: ATPase, H+ transporting, lysosomal V0 subunit a2
    • ATP6V0A4: ATPase, H+ transporting, lysosomal V0 subunit a4
    • ATP6V1B1: ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
    • MT-ATP6: mitochondrially encoded ATP synthase 6
    • TCIRG1: T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
  • Receptor complex
  • Respiratory chain complex II
    • SDHA: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
    • SDHB: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
    • SDHC: succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
    • SDHD: succinate dehydrogenase complex, subunit D, integral membrane protein
  • Retromer complex
    • DCTN1: dynactin 1
    • RAB7A: RAB7A, member RAS oncogene family
    • SLC11A2: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
  • Ribonuclease H2 complex
  • RNA cap binding complex
    • FMR1: fragile X mental retardation 1
  • Sarcoglycan complex
    • SGCB: sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
    • SGCD: sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
    • SGCE: sarcoglycan, epsilon
    • SGCG: sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
  • Ski complex
    • SKIV2L: superkiller viralicidic activity 2-like (S. cerevisiae)
    • TTC37: tetratricopeptide repeat domain 37
  • SMAD protein complex
    • SMAD3: SMAD family member 3
    • SMAD4: SMAD family member 4
  • SMC loading complex
    • NIPBL: Nipped-B homolog (Drosophila)
  • SMN complex
    • SMN2: survival of motor neuron 2, centromeric
  • SMN-Sm protein complex
    • SMN2: survival of motor neuron 2, centromeric
  • Stereocilia ankle link complex
    • USH2A: Usher syndrome 2A (autosomal recessive, mild)
  • SWI/SNF superfamily-type complex
  • Syntrophin complex
    • DMD: dystrophin
  • TCTN-B9D complex
    • CEP290: centrosomal protein 290kDa
  • TORC2 complex
    • PINK1: PTEN induced putative kinase 1
  • Transcriptional repressor complex
    • ELANE: elastase, neutrophil expressed
    • GATA1: GATA binding protein 1 (globin transcription factor 1)
    • SALL1: spalt-like transcription factor 1
    • SKI: SKI proto-oncogene
    • SMARCE1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  • Transcription elongation factor complex
    • CDC73: cell division cycle 73
    • ERCC6: excision repair cross-complementation group 6
    • IKBKAP: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
  • Transcription factor complex
  • Transporter complex
  • Tricarboxylic acid cycle enzyme complex
    • BCKDHA: branched chain keto acid dehydrogenase E1, alpha polypeptide
    • BCKDHB: branched chain keto acid dehydrogenase E1, beta polypeptide
    • DBT: dihydrolipoamide branched chain transacylase E2
  • Troponin complex
    • TNNI3: troponin I type 3 (cardiac)
    • TNNT2: troponin T type 2 (cardiac)
  • TSC1-TSC2 complex
    • NEFL: neurofilament, light polypeptide
    • TSC1: tuberous sclerosis 1
    • TSC2: tuberous sclerosis 2
  • Tubulin complex
    • MAPT: microtubule-associated protein tau
  • T-UTP complex
    • CIRH1A: cirrhosis, autosomal recessive 1A (cirhin)
  • UDP-N-acetylglucosamine transferase complex
    • EXT2: exostosin glycosyltransferase 2
  • WASH complex

Source: Gene Ontology ConsortiumThis link leads to a site outside Genetics Home Reference..

 
Published: April 20, 2015