Hydrolase activity

Hydrolase activity

• ABCB7: ATP-binding cassette, sub-family B (MDR/TAP), member 7
• ABCC2: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
• ABCC6: ATP-binding cassette, sub-family C (CFTR/MRP), member 6
• ABCD1: ATP-binding cassette, sub-family D (ALD), member 1
• ADA: adenosine deaminase
• ADAMTS2: ADAM metallopeptidase with thrombospondin type 1 motif, 2
• AGA: aspartylglucosaminidase
• AHCY: adenosylhomocysteinase
• AMPD1: adenosine monophosphate deaminase 1 (isoform M)
• ANG: angiogenin, ribonuclease, RNase A family, 5
• APTX: aprataxin
• ARG1: arginase, liver
• ARSA: arylsulfatase A
• ASPA: aspartoacylase (Canavan disease)
• ATP1A2: ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide
• ATP1A3: ATPase, Na+/K+ transporting, alpha 3 polypeptide
• ATP2A2: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
• ATP2B2: ATPase, Ca++ transporting, plasma membrane 2
• ATP7A: ATPase, Cu++ transporting, alpha polypeptide
• ATP7B: ATPase, Cu++ transporting, beta polypeptide
• ATRX: alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)
• BLM: Bloom syndrome, RecQ helicase-like
• BRIP1: BRCA1 interacting protein C-terminal helicase 1
• CFTR: cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
• DIRAS3: DIRAS family, GTP-binding RAS-like 3
• DNM2: dynamin 2
• EPM2A: epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• ERAP1: endoplasmic reticulum aminopeptidase 1
• ERCC6: excision repair cross-complementing rodent repair deficiency, complementation group 6
• EYA1: eyes absent homolog 1 (Drosophila)
• F2: coagulation factor II (thrombin)
• F9: coagulation factor IX
• FAH: fumarylacetoacetate hydrolase (fumarylacetoacetase)
• FUCA1: fucosidase, alpha-L- 1, tissue
• GCH1: GTP cyclohydrolase 1
• GLA: galactosidase, alpha
• GNAS: GNAS complex locus
• HEXB: hexosaminidase B (beta polypeptide)
• IDS: iduronate 2-sulfatase
• IDUA: iduronidase, alpha-L-
• KIF1B: kinesin family member 1B
• LPL: lipoprotein lipase
• MAN2B1: mannosidase, alpha, class 2B, member 1
• MANBA: mannosidase, beta A, lysosomal
• MMP20: matrix metallopeptidase 20
• MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
• MSH6: mutS homolog 6 (E. coli)
• MT-ATP6: mitochondrially encoded ATP synthase 6
• MTM1: myotubularin 1
• MTMR2: myotubularin related protein 2
• MUTYH: mutY homolog (E. coli)
• MYH7: myosin, heavy chain 7, cardiac muscle, beta
• MYO6: myosin VI
• MYO7A: myosin VIIA
• NCF1: neutrophil cytosolic factor 1
• OCRL: oculocerebrorenal syndrome of Lowe
• OPA1: optic atrophy 1 (autosomal dominant)
• PCSK9: proprotein convertase subtilisin/kexin type 9
• PROC: protein C (inactivator of coagulation factors Va and VIIIa)
• PSEN1: presenilin 1
• PTEN: phosphatase and tensin homolog
• PTPN11: protein tyrosine phosphatase, non-receptor type 11
• RAB7A: RAB7A, member RAS oncogene family
• RAD50: RAD50 homolog (S. cerevisiae)
• RAD51: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
• RECQL4: RecQ protein-like 4
• SEPT9: septin 9
• SETX: senataxin
• SMARCAL1: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
• SMC1A: structural maintenance of chromosomes 1A
• SMC3: structural maintenance of chromosomes 3
• SMPD1: sphingomyelin phosphodiesterase 1, acid lysosomal
• SPAST: spastin
• SPG7: spastic paraplegia 7 (pure and complicated autosomal recessive)
• TMPRSS3: transmembrane protease, serine 3
• TOR1A: torsin family 1, member A (torsin A)
• UCHL1: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• USP9Y: ubiquitin specific peptidase 9, Y-linked
• VCP: valosin-containing protein
• WRN: Werner syndrome, RecQ helicase-like

Source: Gene Ontology Consortium (June 2009).